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Eukaryotic TYW1 Is a Radical SAM Flavoenzyme

[Image: see text] TYW1 is a radical S-adenosyl-l-methionine (SAM) enzyme that catalyzes the condensation of pyruvate and N-methylguanosine-containing tRNA(Phe), forming 4-demethylwyosine-containing tRNA(Phe). Homologues of TYW1 are found in both archaea and eukarya; archaeal homologues consist of a...

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Detalles Bibliográficos
Autores principales:	Young, Anthony P., Bandarian, Vahe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8941971/ https://www.ncbi.nlm.nih.gov/pubmed/34184886 http://dx.doi.org/10.1021/acs.biochem.1c00349

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