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Widespread association of ERα with RMRP and tRNA genes in MCF-7 cells and breast cancers
tRNA gene transcription by RNA polymerase III (Pol III) is a tightly regulated process, but dysregulated Pol III transcription is widely observed in cancers. Approximately 75% of all breast cancers are positive for expression of Estrogen Receptor alpha (ERα), which acts as a key driver of disease. M...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier/North-Holland
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942118/ https://www.ncbi.nlm.nih.gov/pubmed/35143945 http://dx.doi.org/10.1016/j.gene.2022.146280 |