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Widespread association of ERα with RMRP and tRNA genes in MCF-7 cells and breast cancers

tRNA gene transcription by RNA polymerase III (Pol III) is a tightly regulated process, but dysregulated Pol III transcription is widely observed in cancers. Approximately 75% of all breast cancers are positive for expression of Estrogen Receptor alpha (ERα), which acts as a key driver of disease. M...

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Detalles Bibliográficos
Autores principales: Malcolm, Jodie R., Leese, Natasha K., Lamond-Warner, Philippa I., Brackenbury, William J., White, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942118/
https://www.ncbi.nlm.nih.gov/pubmed/35143945
http://dx.doi.org/10.1016/j.gene.2022.146280