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Widespread association of ERα with RMRP and tRNA genes in MCF-7 cells and breast cancers

tRNA gene transcription by RNA polymerase III (Pol III) is a tightly regulated process, but dysregulated Pol III transcription is widely observed in cancers. Approximately 75% of all breast cancers are positive for expression of Estrogen Receptor alpha (ERα), which acts as a key driver of disease. M...

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Detalles Bibliográficos
Autores principales:	Malcolm, Jodie R., Leese, Natasha K., Lamond-Warner, Philippa I., Brackenbury, William J., White, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier/North-Holland 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942118/ https://www.ncbi.nlm.nih.gov/pubmed/35143945 http://dx.doi.org/10.1016/j.gene.2022.146280

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