Modelling aptamers with nucleic acid mimics (NAM): From sequence to three-dimensional docking

Aptamers are single-stranded oligonucleotides, formerly evolved by Systematic Evolution of Ligands by EXponential enrichment (SELEX), that fold into functional three-dimensional structures. Such conformation is crucial for aptamers’ ability to bind to a target with high affinity and specificity. Unn...

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Detalles Bibliográficos
Autores principales: Oliveira, Ricardo, Pinho, Eva, Sousa, Ana Luísa, Dias, Óscar, Azevedo, Nuno Filipe, Almeida, Carina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942228/
https://www.ncbi.nlm.nih.gov/pubmed/35320268
http://dx.doi.org/10.1371/journal.pone.0264701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942228/
https://www.ncbi.nlm.nih.gov/pubmed/35320268
http://dx.doi.org/10.1371/journal.pone.0264701

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