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Modelling aptamers with nucleic acid mimics (NAM): From sequence to three-dimensional docking
Aptamers are single-stranded oligonucleotides, formerly evolved by Systematic Evolution of Ligands by EXponential enrichment (SELEX), that fold into functional three-dimensional structures. Such conformation is crucial for aptamers’ ability to bind to a target with high affinity and specificity. Unn...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942228/ https://www.ncbi.nlm.nih.gov/pubmed/35320268 http://dx.doi.org/10.1371/journal.pone.0264701 |