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A CRISPR-Cas9 screen reveals a role for WD repeat-containing protein 81 (WDR81) in the entry of late penetrating viruses

Successful initiation of infection by many different viruses requires their uptake into the endosomal compartment. While some viruses exit this compartment early, others must reach the degradative, acidic environment of the late endosome. Mammalian orthoreovirus (reovirus) is one such late penetrati...

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Detalles Bibliográficos
Autores principales: Snyder, Anthony J., Abad, Andrew T., Danthi, Pranav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942271/
https://www.ncbi.nlm.nih.gov/pubmed/35320319
http://dx.doi.org/10.1371/journal.ppat.1010398