A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration

Currently, there is no pharmacological treatment targeting defective tissue repair in chronic disease. Here, we used a transcriptomics-guided drug target discovery strategy using gene signatures of smoking-associated chronic obstructive pulmonary disease (COPD) and from mice chronically exposed to c...

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Detalles Bibliográficos
Autores principales: Wu, Xinhui, Bos, I. Sophie T., Conlon, Thomas M., Ansari, Meshal, Verschut, Vicky, van der Koog, Luke, Verkleij, Lars A., D’Ambrosi, Angela, Matveyenko, Aleksey, Schiller, Herbert B., Königshoff, Melanie, Schmidt, Martina, Kistemaker, Loes E. M., Yildirim, Ali Önder, Gosens, Reinoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942365/
https://www.ncbi.nlm.nih.gov/pubmed/35319981
http://dx.doi.org/10.1126/sciadv.abj9949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942365/
https://www.ncbi.nlm.nih.gov/pubmed/35319981
http://dx.doi.org/10.1126/sciadv.abj9949

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