Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA

Individuals frequently differ in their behavioral and cognitive responses to stress. However, whether motivation is differently affected by acute stress in different individuals remains to be established. By exploiting natural variation in trait anxiety in outbred Wistar rats, we show that acute str...

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Detalles Bibliográficos
Autores principales: Zalachoras, Ioannis, Astori, Simone, Meijer, Mandy, Grosse, Jocelyn, Zanoletti, Olivia, de Suduiraut, Isabelle Guillot, Deussing, Jan M., Sandi, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942367/
https://www.ncbi.nlm.nih.gov/pubmed/35319997
http://dx.doi.org/10.1126/sciadv.abj9019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942367/
https://www.ncbi.nlm.nih.gov/pubmed/35319997
http://dx.doi.org/10.1126/sciadv.abj9019

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