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Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA
Individuals frequently differ in their behavioral and cognitive responses to stress. However, whether motivation is differently affected by acute stress in different individuals remains to be established. By exploiting natural variation in trait anxiety in outbred Wistar rats, we show that acute str...
Autores principales: | Zalachoras, Ioannis, Astori, Simone, Meijer, Mandy, Grosse, Jocelyn, Zanoletti, Olivia, de Suduiraut, Isabelle Guillot, Deussing, Jan M., Sandi, Carmen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942367/ https://www.ncbi.nlm.nih.gov/pubmed/35319997 http://dx.doi.org/10.1126/sciadv.abj9019 |
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