Cargando…

HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway

Diabetic retinopathy (DR) is a serious complication of diabetes mellitus and currently one of the major causes of blindness. Several previous studies have demonstrated that autophagy, which is regulated by HMGB1 (high mobility group box 1), is involved in DR development. However, the role of autopha...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, Lujia, Liang, Liang, Zhang, Shaochong, Yang, Jinglu, Yue, Yanan, Zhang, Xuedong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942416/
https://www.ncbi.nlm.nih.gov/pubmed/34024230
http://dx.doi.org/10.1080/15548627.2021.1926655