Cargando…

Autophagy and ALS: mechanistic insights and therapeutic implications

Mechanisms of protein homeostasis are crucial for overseeing the clearance of misfolded and toxic proteins over the lifetime of an organism, thereby ensuring the health of neurons and other cells of the central nervous system. The highly conserved pathway of autophagy is particularly necessary for p...

Descripción completa

Detalles Bibliográficos
Autores principales: Chua, Jason P., De Calbiac, Hortense, Kabashi, Edor, Barmada, Sami J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942428/
https://www.ncbi.nlm.nih.gov/pubmed/34057020
http://dx.doi.org/10.1080/15548627.2021.1926656