Oral delivery of the intracellular domain of the insulinoma-associated protein 2 (IA-2ic) by bacterium-like particles (BLPs) prevents type 1 diabetes mellitus in NOD mice

Antigen-specific immune tolerance, which possesses great potential in preventing or curing type 1 diabetes mellitus (T1DM), can be induced by oral vaccination with T1DM-related autoantigens. However, direct administration of autoantigens via oral route exhibits a low tolerance-inducing effect as a r...

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Detalles Bibliográficos
Autores principales: Mao, Ruifeng, Yang, Menglan, Yang, Rui, Chen, Yingying, Diao, Enjie, Zhang, Tong, Li, Dengchao, Chang, Xin, Chi, Zhenjing, Wang, Yefu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942491/
https://www.ncbi.nlm.nih.gov/pubmed/35311607
http://dx.doi.org/10.1080/10717544.2022.2053760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942491/
https://www.ncbi.nlm.nih.gov/pubmed/35311607
http://dx.doi.org/10.1080/10717544.2022.2053760

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