Esco2 and cohesin regulate CRL4 ubiquitin ligase ddb1 expression and thalidomide teratogenicity

Cornelia de Lange syndrome (CdLS) and Roberts syndrome (RBS) are severe developmental maladies that arise from mutation of cohesin (including SMC3, CdLS) and ESCO2 (RBS). Though ESCO2 activates cohesin, CdLS and RBS etiologies are currently considered non-synonymous and for which pharmacological tre...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanchez, Annie C., Thren, Elise D., Iovine, M. Kathryn, Skibbens, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942496/
https://www.ncbi.nlm.nih.gov/pubmed/34989322
http://dx.doi.org/10.1080/15384101.2021.2023304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942496/
https://www.ncbi.nlm.nih.gov/pubmed/34989322
http://dx.doi.org/10.1080/15384101.2021.2023304

Ejemplares similares