Lipidated Calcitonin Gene-Related Peptide (CGRP) Peptide Antagonists Retain CGRP Receptor Activity and Attenuate CGRP Action In Vivo

Signaling through calcitonin gene-related peptide (CGRP) receptors is associated with pain, migraine, and energy expenditure. Small molecule and monoclonal antibody CGRP receptor antagonists that block endogenous CGRP action are in clinical use as anti-migraine therapies. By comparison, the potentia...

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Detalles Bibliográficos
Autores principales: Jamaluddin, Aqfan, Chuang, Chia-Lin, Williams, Elyse T., Siow, Andrew, Yang, Sung Hyun, Harris, Paul W. R., Petersen, Jakeb S. S. M., Bower, Rebekah L., Chand, Shanan, Brimble, Margaret A., Walker, Christopher S., Hay, Debbie L., Loomes, Kerry M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942775/
https://www.ncbi.nlm.nih.gov/pubmed/35341216
http://dx.doi.org/10.3389/fphar.2022.832589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942775/
https://www.ncbi.nlm.nih.gov/pubmed/35341216
http://dx.doi.org/10.3389/fphar.2022.832589

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