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Regulation of SARS CoV-2 host factors in the kidney and heart in rats with 5/6 nephrectomy—effects of salt, ARB, DPP4 inhibitor and SGLT2 blocker

BACKGROUND: Host factors such as angiotensin-converting enzyme 2 (ACE2) and the transmembrane protease, serine-subtype-2 (TMPRSS2) are important factors for SARS-CoV-2 infection. Clinical and pre-clinical studies demonstrated that RAAS-blocking agents can be safely used during a SARS-CoV-2 infection...

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Detalles Bibliográficos
Autores principales: Xiong, Yingquan, Delic, Denis, Zeng, Shufei, Chen, Xin, Chu, Chang, Hasan, Ahmed A., Krämer, Bernhard K., Klein, Thomas, Yin, Lianghong, Hocher, Berthold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942812/
https://www.ncbi.nlm.nih.gov/pubmed/35331159
http://dx.doi.org/10.1186/s12882-022-02747-1