Interplay between nuclear factor-κB, p38 MAPK, and glucocorticoid receptor signaling synergistically induces functional TLR2 in lung epithelial cells

While glucocorticoids act via the glucocorticoid receptor (GR; NR3C1) to reduce the expression of many inflammatory genes, repression is not an invariable outcome. Here, we explore synergy occurring between synthetic glucocorticoids (dexamethasone and budesonide) and proinflammatory cytokines (IL1B...

Descripción completa

Detalles Bibliográficos
Autores principales: Bansal, Akanksha, Mostafa, Mahmoud M., Kooi, Cora, Sasse, Sarah K., Michi, Aubrey N., Shah, Suharsh V., Leigh, Richard, Gerber, Anthony N., Newton, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942839/
https://www.ncbi.nlm.nih.gov/pubmed/35189144
http://dx.doi.org/10.1016/j.jbc.2022.101747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942839/
https://www.ncbi.nlm.nih.gov/pubmed/35189144
http://dx.doi.org/10.1016/j.jbc.2022.101747

Ejemplares similares