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Interplay between nuclear factor-κB, p38 MAPK, and glucocorticoid receptor signaling synergistically induces functional TLR2 in lung epithelial cells

While glucocorticoids act via the glucocorticoid receptor (GR; NR3C1) to reduce the expression of many inflammatory genes, repression is not an invariable outcome. Here, we explore synergy occurring between synthetic glucocorticoids (dexamethasone and budesonide) and proinflammatory cytokines (IL1B...

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Detalles Bibliográficos
Autores principales:	Bansal, Akanksha, Mostafa, Mahmoud M., Kooi, Cora, Sasse, Sarah K., Michi, Aubrey N., Shah, Suharsh V., Leigh, Richard, Gerber, Anthony N., Newton, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942839/ https://www.ncbi.nlm.nih.gov/pubmed/35189144 http://dx.doi.org/10.1016/j.jbc.2022.101747

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