MSC secreted extracellular vesicles carrying TGF-beta upregulate Smad 6 expression and promote the regrowth of neurons in spinal cord injured rats

Mesenchymal stem cells (MSCs) constitute a promising therapy for spinal cord injury (SCI) because they can provide a favorable environment for the regrowth of neurons by inhibiting receptor-regulated Smads (R-Smads) expression in endogenous neural stem cells (NSCs). However, their mechanism of actio...

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Detalles Bibliográficos
Autores principales: Han, Tianyu, Song, Peiwen, Wu, Zuomeng, Xiang, Xia, Liu, Yunlei, Wang, Ying, Fang, Huang, Niu, Yang, Shen, Cailiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942898/
https://www.ncbi.nlm.nih.gov/pubmed/34449013
http://dx.doi.org/10.1007/s12015-021-10219-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942898/
https://www.ncbi.nlm.nih.gov/pubmed/34449013
http://dx.doi.org/10.1007/s12015-021-10219-6

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