High Glucose and Hypoxia-Mediated Damage to Human Brain Microvessel Endothelial Cells Induces an Altered, Pro-Inflammatory Phenotype in BV-2 Microglia In Vitro

Diabetes is strongly linked to the development of Alzheimer’s disease (AD), though the mechanisms for this enhanced risk are unclear. Because vascular inflammation is a consistent feature of both diabetes and AD, the cerebral microcirculation could be a key target for the effects of diabetes in the...

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Detalles Bibliográficos
Autores principales: Iannucci, Jaclyn, Rao, Haripriya Vittal, Grammas, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942976/
https://www.ncbi.nlm.nih.gov/pubmed/33136275
http://dx.doi.org/10.1007/s10571-020-00987-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942976/
https://www.ncbi.nlm.nih.gov/pubmed/33136275
http://dx.doi.org/10.1007/s10571-020-00987-z

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