Altered proteome in translation initiation fidelity defective eIF5(G31R) mutant causes oxidative stress and DNA damage

The recognition of the AUG start codon and selection of an open reading frame (ORF) is fundamental to protein biosynthesis. Defect in the fidelity of start codon selection adversely affect proteome and have a pleiotropic effect on cellular function. Using proteomic techniques, we identified differen...

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Detalles Bibliográficos
Autores principales: Ram, Anup Kumar, Mallik, Monalisha, Reddy, R. Rajendra, Suryawanshi, Amol Ratnakar, Alone, Pankaj V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943034/
https://www.ncbi.nlm.nih.gov/pubmed/35322093
http://dx.doi.org/10.1038/s41598-022-08857-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943034/
https://www.ncbi.nlm.nih.gov/pubmed/35322093
http://dx.doi.org/10.1038/s41598-022-08857-y

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