Neuron-recognizable characteristics of peptides recombined using a neuronal binding domain of botulinum neurotoxin

Recombinant peptides were designed using the C-terminal domain (receptor binding domain, RBD) and its subdomain (peptide A2) of a heavy chain of botulinum neurotoxin A-type 1 (BoNT/A1), which can bind to the luminal domain of synaptic vesicle glycoprotein 2C (SV2C-LD). Peptide A2- or RBD-containing...

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Detalles Bibliográficos
Autores principales: Kim, Hye Rin, Jung, Younghun, Shin, Jonghyeok, Park, Myungseo, Kweon, Dae-Hyuk, Ban, Choongjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943039/
https://www.ncbi.nlm.nih.gov/pubmed/35322139
http://dx.doi.org/10.1038/s41598-022-09145-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943039/
https://www.ncbi.nlm.nih.gov/pubmed/35322139
http://dx.doi.org/10.1038/s41598-022-09145-5

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