Alginate oligosaccharides enhance diffusion and activity of colistin in a mucin-rich environment

In a number of chronic respiratory diseases e.g. cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD), the production of viscous mucin reduces pulmonary function and represents an effective barrier to diffusion of inhaled therapies e.g. antibiotics. Here, a 2-compartment Transwell m...

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Detalles Bibliográficos
Autores principales: Stokniene, Joana, Varache, Mathieu, Rye, Philip D., Hill, Katja E., Thomas, David W., Ferguson, Elaine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943044/
https://www.ncbi.nlm.nih.gov/pubmed/35322119
http://dx.doi.org/10.1038/s41598-022-08927-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943044/
https://www.ncbi.nlm.nih.gov/pubmed/35322119
http://dx.doi.org/10.1038/s41598-022-08927-1

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