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Alginate oligosaccharides enhance diffusion and activity of colistin in a mucin-rich environment
In a number of chronic respiratory diseases e.g. cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD), the production of viscous mucin reduces pulmonary function and represents an effective barrier to diffusion of inhaled therapies e.g. antibiotics. Here, a 2-compartment Transwell m...
Autores principales: | Stokniene, Joana, Varache, Mathieu, Rye, Philip D., Hill, Katja E., Thomas, David W., Ferguson, Elaine L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943044/ https://www.ncbi.nlm.nih.gov/pubmed/35322119 http://dx.doi.org/10.1038/s41598-022-08927-1 |
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