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In-vitro engineered human cerebral tissues mimic pathological circuit disturbances in 3D

In-vitro modeling of brain network disorders such as epilepsy remains a major challenge. A critical step is to develop an experimental approach that enables recapitulation of in-vivo-like three-dimensional functional complexity while allowing local modulation of the neuronal networks. Here, by promo...

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Detalles Bibliográficos
Autores principales: Saberi, Aref, Aldenkamp, Albert P., Kurniawan, Nicholas A., Bouten, Carlijn V. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943047/
https://www.ncbi.nlm.nih.gov/pubmed/35322168
http://dx.doi.org/10.1038/s42003-022-03203-4