A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V

C-type inactivation is of great physiological importance in voltage-activated K(+) channels (Kv), but its structural basis remains unresolved. Knowledge about C-type inactivation has been largely deduced from the bacterial K(+) channel KcsA, whose selectivity filter constricts under inactivating con...

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Detalles Bibliográficos
Autores principales: Rohaim, Ahmed, Vermeulen, Bram J. A., Li, Jing, Kümmerer, Felix, Napoli, Federico, Blachowicz, Lydia, Medeiros-Silva, João, Roux, Benoît, Weingarth, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943062/
https://www.ncbi.nlm.nih.gov/pubmed/35322021
http://dx.doi.org/10.1038/s41467-022-28866-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943062/
https://www.ncbi.nlm.nih.gov/pubmed/35322021
http://dx.doi.org/10.1038/s41467-022-28866-9

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