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Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP

Our cluster analysis of the Cancer Genome Atlas for co-expression of HSP27 and CRYAB in breast cancer patients identified three patient groups based on their expression level combination (high HSP27 + low CRYAB; low HSP27 + high CRYAB; similar HSP27 + CRYAB). Our analyses also suggest that there is...

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Detalles Bibliográficos
Autores principales: Quinlan, Philip R., Figeuredo, Grazziela, Mongan, Nigel, Jordan, Lee B., Bray, Susan E., Sreseli, Roman, Ashfield, Alison, Mitsch, Jurgen, van den Ijssel, Paul, Thompson, Alastair M., Quinlan, Roy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943080/
https://www.ncbi.nlm.nih.gov/pubmed/35235182
http://dx.doi.org/10.1007/s12192-022-01258-0