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Cryo-EM structure of transmembrane AAA+ protease FtsH in the ADP state

AAA+ proteases regulate numerous physiological and cellular processes through tightly regulated proteolytic cleavage of protein substrates driven by ATP hydrolysis. FtsH is the only known family of membrane-anchored AAA+ proteases essential for membrane protein quality control. Although a spiral sta...

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Detalles Bibliográficos
Autores principales: Liu, Wu, Schoonen, Martien, Wang, Tong, McSweeney, Sean, Liu, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943139/
https://www.ncbi.nlm.nih.gov/pubmed/35322207
http://dx.doi.org/10.1038/s42003-022-03213-2