Activation of lysosomal mediated cell death in the course of autophagy by mTORC1 inhibitor

Lysosomal biogenesis plays a vital role in cell fate. Under certain conditions, excessive lysosomal biogenesis leads to susceptibility for lysosomal membrane permeabilization resulting in various pathological conditions including cell death. In cancer cells apoptosis machinery becomes dysregulated d...

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Detalles Bibliográficos
Autores principales: Khan, Sameer Ullah, Pathania, Anup Singh, Wani, Abubakar, Fatima, Kaneez, Mintoo, Mubashir Javed, Hamza, Baseerat, Paddar, Masroor Ahmad, Bhumika, Wadhwa, Anand, Loveleena Kour, Maqbool, Mir Shahid, Mir, Sameer Ahmad, Kour, Jaspreet, Venkateswarlu, Vunnam, Mondhe, Dilip Manikrao, Sawant, Sanghapal D., Malik, Fayaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943151/
https://www.ncbi.nlm.nih.gov/pubmed/35322026
http://dx.doi.org/10.1038/s41598-022-07955-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943151/
https://www.ncbi.nlm.nih.gov/pubmed/35322026
http://dx.doi.org/10.1038/s41598-022-07955-1

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