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Lower novelty-related locus coeruleus function is associated with Aβ-related cognitive decline in clinically healthy individuals

Animal and human imaging research reported that the presence of cortical Alzheimer’s Disease’s (AD) neuropathology, beta-amyloid and neurofibrillary tau, is associated with altered neuronal activity and circuitry failure, together facilitating clinical progression. The locus coeruleus (LC), one of t...

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Detalles Bibliográficos
Autores principales: Prokopiou, Prokopis C., Engels-Domínguez, Nina, Papp, Kathryn V., Scott, Matthew R., Schultz, Aaron P., Schneider, Christoph, Farrell, Michelle E., Buckley, Rachel F., Quiroz, Yakeel T., El Fakhri, Georges, Rentz, Dorene M., Sperling, Reisa A., Johnson, Keith A., Jacobs, Heidi I. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943159/
https://www.ncbi.nlm.nih.gov/pubmed/35322012
http://dx.doi.org/10.1038/s41467-022-28986-2