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Lower novelty-related locus coeruleus function is associated with Aβ-related cognitive decline in clinically healthy individuals
Animal and human imaging research reported that the presence of cortical Alzheimer’s Disease’s (AD) neuropathology, beta-amyloid and neurofibrillary tau, is associated with altered neuronal activity and circuitry failure, together facilitating clinical progression. The locus coeruleus (LC), one of t...
Autores principales: | Prokopiou, Prokopis C., Engels-Domínguez, Nina, Papp, Kathryn V., Scott, Matthew R., Schultz, Aaron P., Schneider, Christoph, Farrell, Michelle E., Buckley, Rachel F., Quiroz, Yakeel T., El Fakhri, Georges, Rentz, Dorene M., Sperling, Reisa A., Johnson, Keith A., Jacobs, Heidi I. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943159/ https://www.ncbi.nlm.nih.gov/pubmed/35322012 http://dx.doi.org/10.1038/s41467-022-28986-2 |
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