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Unveiling RCOR1 as a rheostat at transcriptionally permissive chromatin

RCOR1 is a known transcription repressor that recruits and positions LSD1 and HDAC1/2 on chromatin to erase histone methylation and acetylation. However, there is currently an incomplete understanding of RCOR1’s range of localization and function. Here, we probe RCOR1’s distribution on a genome-wide...

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Detalles Bibliográficos
Autores principales: Rivera, Carlos, Lee, Hun-Goo, Lappala, Anna, Wang, Danni, Noches, Verónica, Olivares-Costa, Montserrat, Sjöberg-Herrera, Marcela, Lee, Jeannie T., Andrés, María Estela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943175/
https://www.ncbi.nlm.nih.gov/pubmed/35322029
http://dx.doi.org/10.1038/s41467-022-29261-0