Contrasting roles for G-quadruplexes in regulating human Bcl-2 and virus homologues KSHV KS-Bcl-2 and EBV BHRF1

Herpesviruses are known to acquire several genes from their hosts during evolution. We found that a significant proportion of virus homologues encoded by HSV-1, HSV-2, EBV and KSHV and their human counterparts contain G-quadruplex motifs in their promoters. We sought to understand the role of G-quad...

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Detalles Bibliográficos
Autores principales: Kumar, Shivani, Ramamurthy, Chitteti, Choudhary, Divya, Sekar, Aashika, Patra, Anupam, Bhavesh, Neel Sarovar, Vivekanandan, Perumal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943185/
https://www.ncbi.nlm.nih.gov/pubmed/35322051
http://dx.doi.org/10.1038/s41598-022-08161-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943185/
https://www.ncbi.nlm.nih.gov/pubmed/35322051
http://dx.doi.org/10.1038/s41598-022-08161-9

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