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Contrasting roles for G-quadruplexes in regulating human Bcl-2 and virus homologues KSHV KS-Bcl-2 and EBV BHRF1
Herpesviruses are known to acquire several genes from their hosts during evolution. We found that a significant proportion of virus homologues encoded by HSV-1, HSV-2, EBV and KSHV and their human counterparts contain G-quadruplex motifs in their promoters. We sought to understand the role of G-quad...
Autores principales: | Kumar, Shivani, Ramamurthy, Chitteti, Choudhary, Divya, Sekar, Aashika, Patra, Anupam, Bhavesh, Neel Sarovar, Vivekanandan, Perumal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943185/ https://www.ncbi.nlm.nih.gov/pubmed/35322051 http://dx.doi.org/10.1038/s41598-022-08161-9 |
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