The paradox of Prader-Willi syndrome revisited: Making sense of the phenotype

Prader-Willi syndrome arises as a consequence of absent paternal copies of maternally imprinted genes at 15q11-13. Such gender-of-origin imprinted genes are expressed in the brain and also in mammalian placenta where paternally expressed imprinted genes drive foetal nutritional demand. We hypothesis...

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Detalles Bibliográficos
Autores principales: Holland, Anthony, Manning, Katie, Whittington, Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943243/
https://www.ncbi.nlm.nih.gov/pubmed/35316681
http://dx.doi.org/10.1016/j.ebiom.2022.103952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943243/
https://www.ncbi.nlm.nih.gov/pubmed/35316681
http://dx.doi.org/10.1016/j.ebiom.2022.103952

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