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Vascular remodelling in idiopathic pulmonary fibrosis patients and its detrimental effect on lung physiology: potential role of endothelial-to-mesenchymal transition

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible fibrotic interstitial lung disease. We performed size-based quantitation of pulmonary arterial remodelling in IPF and examined the role of endothelial-to-mesenchymal transition (EndMT) and effects on lung physiology. METH...

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Detalles Bibliográficos
Autores principales: Gaikwad, Archana Vijay, Lu, Wenying, Dey, Surajit, Bhattarai, Prem, Chia, Collin, Larby, Josie, Haug, Greg, Myers, Stephen, Jaffar, Jade, Westall, Glen, Singhera, Gurpreet Kaur, Hackett, Tillie-Louise, Markos, James, Eapen, Mathew Suji, Sohal, Sukhwinder Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943284/
https://www.ncbi.nlm.nih.gov/pubmed/35350273
http://dx.doi.org/10.1183/23120541.00571-2021