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Heat shock protein 60 couples an oxidative stress-responsive p38/MK2 signaling and NF-κB survival machinery in cancer cells

Mitochondria communicate with other cellular compartments via the secretion of protein factors. Here, we report an unexpected messenger role for heat shock protein 60 (HSP60) as a mitochondrial-releasing protein factor that couples stress-sensing signaling and cell survival machineries. We show that...

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Detalles Bibliográficos
Autores principales: Min, Seongchun, Kim, Ji Yeon, Cho, Hyo Min, Park, Sujin, Hwang, Ji Min, You, Hyejin, Chan Chae, Young, Lee, Won-Jae, Sun, Woong, Kang, Dongmin, Lee, Sanghyuk, Kang, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943299/
https://www.ncbi.nlm.nih.gov/pubmed/35316673
http://dx.doi.org/10.1016/j.redox.2022.102293