Not making the cut: Techniques to prevent RNA cleavage in structural studies of RNase–RNA complexes

RNases are varied in the RNA structures and sequences they target for cleavage and are an important type of enzyme in cells. Despite the numerous examples of RNases known, and of those with determined three-dimensional structures, relatively few examples exist with the RNase bound to intact cognate...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Seth P., Goossen, Christian, Lewis, Sean D., Delaney, Annie M., Gleghorn, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943300/
https://www.ncbi.nlm.nih.gov/pubmed/35340590
http://dx.doi.org/10.1016/j.yjsbx.2022.100066