Development of Cas12a-Based Cell-Free Small-Molecule Biosensors via Allosteric Regulation of CRISPR Array Expression

[Image: see text] Cell-free biosensors can detect various molecules, thus promising to transform the landscape of diagnostics. Here, we developed a simple, rapid, sensitive, and field-deployable small-molecule detection platform based on allosteric transcription factor (aTF)-regulated expression of...

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Detalles Bibliográficos
Autores principales: Mahas, Ahmed, Wang, Qiaochu, Marsic, Tin, Mahfouz, Magdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943526/
https://www.ncbi.nlm.nih.gov/pubmed/35266687
http://dx.doi.org/10.1021/acs.analchem.1c04332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943526/
https://www.ncbi.nlm.nih.gov/pubmed/35266687
http://dx.doi.org/10.1021/acs.analchem.1c04332

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