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Glaucocalyxin A alleviates lipopolysaccharide-induced inflammation and apoptosis in pulmonary microvascular endothelial cells and permeability injury by inhibiting STAT3 signaling

Glaucocalyxin A (GLA), an ent-kauranoid diterpene derived from Rabdosia japonica var. glaucocalyx, possesses antibacterial, anti-oxidative and anti-neuroinflammatory properties. The present study aimed to investigate the potential mechanisms underlying GLA in the pathogenesis of pneumonia. Human pul...

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Detalles Bibliográficos
Autores principales: Cao, Jianwei, Liu, Meiling, Feng, Shufang, Li, Yingying, Zheng, Kaijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943557/
https://www.ncbi.nlm.nih.gov/pubmed/35369532
http://dx.doi.org/10.3892/etm.2022.11242