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Quantifying epigenetic modulation of nucleosome breathing by high-throughput AFM imaging
Nucleosomes are the basic units of chromatin and critical for storage and expression of eukaryotic genomes. Chromatin accessibility and gene readout are heavily regulated by epigenetic marks, in which post-translational modifications of histones play a key role. However, the mode of action and the s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943691/ https://www.ncbi.nlm.nih.gov/pubmed/35065917 http://dx.doi.org/10.1016/j.bpj.2022.01.014 |