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Mechanical force can enhance c-Src kinase activity by impairing autoinhibition
Cellular mechanosensing is pivotal for virtually all biological processes, and many molecular mechano-sensors and their way of function are being uncovered. In this work, we suggest that c-Src kinase acts as a direct mechano-sensor. c-Src is responsible for, among others, cell proliferation, and sho...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943751/ https://www.ncbi.nlm.nih.gov/pubmed/35120901 http://dx.doi.org/10.1016/j.bpj.2022.01.028 |