1α,25(OH)(2)D(3) reverses exhaustion and enhances antitumor immunity of human cytotoxic T cells

BACKGROUND: Epidemiological surveys have revealed that low serum vitamin D level was correlated with increased risk of tumors. Dysfunctional T cells in patients with tumor are characterized as exhausted with high levels of immune checkpoint receptors (ICRs). However, whether the reduced level of vit...

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Detalles Bibliográficos
Autores principales: Li, Peng, Zhu, Xinhai, Cao, Guangchao, Wu, Ruan, Li, Ke, Yuan, Wenhui, Chen, Biyun, Sun, Guodong, Xia, Xichun, Zhang, Hua, Wang, Xiao, Yin, Zhinan, Lu, Ligong, Gao, Yunfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943781/
https://www.ncbi.nlm.nih.gov/pubmed/35318258
http://dx.doi.org/10.1136/jitc-2021-003477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943781/
https://www.ncbi.nlm.nih.gov/pubmed/35318258
http://dx.doi.org/10.1136/jitc-2021-003477

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