Cargando…

Dl-3-n-butylphthalide alleviates cognitive impairment in amyloid precursor protein/presenilin 1 transgenic mice by regulating the striatal-enriched protein tyrosine phosphatase/ERK/cAMP-response element-binding protein signaling pathway

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive impairment and the deposition of amyloid plaques in the brain. In a transgenic mouse model of AD, cognitive impairment and synaptic dysfunction were revealed to be associated with soluble amyloid oli...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yan, Yang, Wen-Qiang, Yu, Lu, Yang, Jing, Zhu, Hai-Rong, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943801/
https://www.ncbi.nlm.nih.gov/pubmed/35350668
http://dx.doi.org/10.3892/etm.2022.11248