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A hypoxia-activated NO donor for the treatment of myocardial hypoxia injury

As present NO donor drugs cannot localize to release NO at the hypoxic site, along with the short half-life and bidirectional regulation of NO, they are unable to overcome low bioavailability and side effects in the treatment of myocardial hypoxia injury. In this study, we designed and prepared a no...

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Detalles Bibliográficos
Autores principales: Zhou, Wen, Yang, Wanxiang, Fan, Keyu, Hua, Wuyang, Gou, Shaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943891/
https://www.ncbi.nlm.nih.gov/pubmed/35432877
http://dx.doi.org/10.1039/d2sc00048b