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Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy

Cancer microenvironment is critical for tumorigenesis and cancer progression. The extracellular matrix (ECM) interacts with tumor and stromal cells to promote cancer cells proliferation, migration, invasion, angiogenesis and immune evasion. Both ECM itself and ECM stiffening-induced mechanical stimu...

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Detalles Bibliográficos
Autores principales: Jiang, Yangfu, Zhang, Hongying, Wang, Jiao, Liu, Yongliang, Luo, Ting, Hua, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943941/
https://www.ncbi.nlm.nih.gov/pubmed/35331296
http://dx.doi.org/10.1186/s13045-022-01252-0