Cargando…
Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy
Cancer microenvironment is critical for tumorigenesis and cancer progression. The extracellular matrix (ECM) interacts with tumor and stromal cells to promote cancer cells proliferation, migration, invasion, angiogenesis and immune evasion. Both ECM itself and ECM stiffening-induced mechanical stimu...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943941/ https://www.ncbi.nlm.nih.gov/pubmed/35331296 http://dx.doi.org/10.1186/s13045-022-01252-0 |