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Ciclopirox targets cellular bioenergetics and activates ER stress to induce apoptosis in non-small cell lung cancer cells

BACKGROUND: Lung cancer remains a major cause of cancer-related mortality throughout the world at present. Repositioning of existing drugs for other diseases is a promising strategy for cancer therapies, which may rapidly advance potentially promising agents into clinical trials and cut down the cos...

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Detalles Bibliográficos
Autores principales: Lu, Junwan, Li, Yujie, Gong, Shiwei, Wang, Jiaxin, Lu, Xiaoang, Jin, Qiumei, Lu, Bin, Chen, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943949/
https://www.ncbi.nlm.nih.gov/pubmed/35331268
http://dx.doi.org/10.1186/s12964-022-00847-x