Cargando…
Ciclopirox targets cellular bioenergetics and activates ER stress to induce apoptosis in non-small cell lung cancer cells
BACKGROUND: Lung cancer remains a major cause of cancer-related mortality throughout the world at present. Repositioning of existing drugs for other diseases is a promising strategy for cancer therapies, which may rapidly advance potentially promising agents into clinical trials and cut down the cos...
Autores principales: | Lu, Junwan, Li, Yujie, Gong, Shiwei, Wang, Jiaxin, Lu, Xiaoang, Jin, Qiumei, Lu, Bin, Chen, Qin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8943949/ https://www.ncbi.nlm.nih.gov/pubmed/35331268 http://dx.doi.org/10.1186/s12964-022-00847-x |
Ejemplares similares
-
Ciclopirox drives growth arrest and autophagic cell death through STAT3 in gastric cancer cells
por: Chen, Lingyan, et al.
Publicado: (2022) -
Ciclopirox and bortezomib synergistically inhibits glioblastoma multiforme growth via simultaneously enhancing JNK/p38 MAPK and NF-κB signaling
por: Su, Zhipeng, et al.
Publicado: (2021) -
Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer
por: Qi, Jianjun, et al.
Publicado: (2020) -
Oxidative stress regulates cellular bioenergetics in esophageal squamous cell carcinoma cell
por: Zhang, Xiaolong, et al.
Publicado: (2017) -
Delineating the Switch between Senescence and Apoptosis in Cervical Cancer Cells under Ciclopirox Treatment
por: Herrmann, Anja L., et al.
Publicado: (2021)