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Construction of cell factory capable of efficiently converting l-tryptophan into 5-hydroxytryptamine

BACKGROUND: l-Tryptophan (l-Trp) derivatives such as 5-hydroxytryptophan (5-HTP) and 5-hydroxytryptamine (5-HT), N-Acetyl-5-hydroxytryptamine and melatonin are important molecules with pharmaceutical interest. Among, 5-HT is an inhibitory neurotransmitter with proven benefits for treating the sympto...

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Detalles Bibliográficos
Autores principales: Wang, Yingying, Chen, Xueman, Chen, Qiaoyu, Zhou, Ning, Wang, Xin, Zhang, Alei, Chen, Kequan, Ouyang, Pingkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944007/
https://www.ncbi.nlm.nih.gov/pubmed/35331215
http://dx.doi.org/10.1186/s12934-022-01745-0