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Single cell lineage reconstruction using distance-based algorithms and the R package, DCLEAR

BACKGROUND: DCLEAR is an R package used for single cell lineage reconstruction. The advances of CRISPR-based gene editing technologies have enabled the prediction of cell lineage trees based on observed edited barcodes from each cell. However, the performance of existing reconstruction methods of ce...

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Detalles Bibliográficos
Autores principales: Gong, Wuming, Kim, Hyunwoo J., Garry, Daniel J., Kwak, Il-Youp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8944039/
https://www.ncbi.nlm.nih.gov/pubmed/35331133
http://dx.doi.org/10.1186/s12859-022-04633-x